Examples of Enhancing Treatment & Care with Hyperbaric Oxygen Therapy (HBOT): Severe Degloving Wound
This patient was backed over by a car in a driveway. A massive, purulent degloving wound resulted, along with fracture/luxation of the tail and a pelvic fracture. The perianal and preputial skin remained attached and intact. The only surgery performed was plating of the pelvic fracture, and concurrent tail amputation. No wound debridement, grafts, or flaps were ever performed. Hydrotherapy and antibiotics were given along with adjunctive HBOT.
Left: Pre-HBOT (Admission). Right: 2 1/2 months later
HBOT Treatment Dates
April 2: 2 treatments @ 2 ATA
April 4-8: 2 treatments daily @ 2 ATA
April 11 -30 - 2 treatments daily @ 2 ATA
May 3-5: 2 treatments daily @ 2 ATA
May 7: 2 treatments @ 2 ATA
May 10-12: 2 treatments daily @ 2 ATA
May 14: 2 treatments @ 2 ATA
May 17-19: 2 treatments daily @ 2 ATA
May 21: 2 treatments @ 2 ATA
May 24: 2 treatments @ 2 ATA
May 26: 2 treatments @ 2 ATA
May 28: 2 treatments @ 2 ATA
June 1: 2 treatments @ 2 ATA
June 3: 2 treatments @ 2 ATA
June 10: 2 treatments @ 2 ATA
June 17: 2 treatments @ 2 ATA
June 24: 2 treatments @ 2 ATA
HBOT triggers the onset of signal transduction pathways regulating the gene expression of growth factors or their receptors, such as platelet-derived growth factor. This results in up regulation of natural wound healing cascades. (Reference: Bonomo, SR, et al, “Hyperbaric oxygen as a signal transducer: up regulation of platelet derived growth factor-beta receptor in the presence of HBO and PDGF”. Undersea Hyper Med 25:211-216, 1998).
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